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Description

But also, the opposite way is conceivable: if there is a lack of biotin, vitamin B12 cannot fulfil its function in the citrate cycle and remains unused in the tissue possibly leading to the behavioural change of the skin bacteria already discussed

PMID 11313479

And sometimes it fails

The baby exhibited trouble breathing, restlessness, muscle hypertonicity, and hypoglycemia were present

This is particularly important for pregnant women, as the fetus requires adequate vitamin B12 for neurologic development and deficiency can lead to permanent neurological damage