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Assessment and analysis To assess the clinical response photographs were taken at the beginning of the therapy (baseline, i.e., day 0, at each sitting [4th and 8th weeks], and after 4 weeks of last therapy, i.e., at 12th week

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In fact, it was demonstrated that Erastin can potentially activate VDAC channel [50], which results in mitochondrial disruption [51] and lead to apoptotic cell death in gastric [52] and colorectal cancer cells [34]

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