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ROS-induced mitochondrial dysfunction and DNA damage, along with the inhibition of key redox transcription factors such as Nuclear Factor Erythroid 2-Related Factor 2 (NRF2) may contribute to the persistence of symptoms in both ME/CFS and Long COVID (Jarrott et al., 2022)

CD4+ T helper cells stimulated with Dynabeads CD3/CD28 will differentiate into different T helper subsets, depending on the cytokines added during in vitro culture conditions

The double mutant pcs1pcs2 impaired in phytochelatin synthesis and the catabolism of glutathione conjugates 61,62 showed also a WT-like phenotype when exposed to AITC

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have highlighted the crucial regulatory roles of the NRF2 and nuclear factor-kappa B (NF-B) pathways in the oxidative balance homeostasis of mitohormesis 100