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Avoid excessive sun exposure, heavy alcohol consumption, and smoking during a treatment courseall of these increase oxidative stress and directly counteract the antioxidant benefits

METH-activated microglia and astrocytes in the neurovascular unit may promote neurotoxicity and astroglial reactivity and induces BBB integrity loss (Shah et al., 2012

doi: 10.3390/v12070748 143 ParadkarPNTrinidadLVoyseyRDucheminJBWalkerPJ

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This disease is characterized by ataxia and a progressive neurological syndrome and is caused by an unconventional agent known as a prion protein

With an interest in the fundamental biology of neuronal proteostasis, we first asked whether aggresomes form in proteo-stressed C