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Growth hormone receptor expression in tendons: Preclinical work has shown BPC-157 increases GH receptor expression in tendon fibroblasts, which may explain its strong effect on tendon-to-bone healing

PubMed Wilding, J.P.H., Batterham, R.L., Calanna, S., Davies, M., Van Gaal, L.F., Lingvay, I., et al

This is because hemoglobin A1C (a measure of blood sugar control) and sex hormone-binding globulin (SHBG) are inversely correlated: as A1C improves with weight loss, SHBG levels may rise, which can bind more testosterone and reduce the amount that circulates freely in the bloodstream