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In summary, mTOR inhibitors have revealed disease-modifying potential in cancer and genetic disorders such as TSC, but their use is limited by metabolic toxicity

doi: 10.1023/A:1007015027268

Substrates were added to a solution of 250 M NADPH and 0.05 U ml 1 GSH GR

doi: 10.1007/s10858-005-2590-6 Robson, Scott A., Gorbatyuk, Vitaliy Y., Maciejewski, Mark W

In particular, we observed cardioprotective effects of glutathione synthesis stimulation by D,L-propargylglycine and L-cysteine which was manifested in a significant recovery of the contractile function of the heart, increasing NO constitutive synthesis, and inhibition of ROS production in the ischemic myocardium of adult rats (Goshovska et al., 2021)

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