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doi: 10.3892/etm.2023.12267 165 LiuLAkkoyunluM

PMCID: PMC6235926

Melanotan II stimulates MC1R to deepen skin pigmentation through melanin production, and MC4R to modulate sexual arousal and appetite

1484-C PROTEIN EXPRESSION ASSOCIATED WITH ALANINE AMINOTRANSFERASE INCREASE DURING BEPIROVIRSEN TREATMENT: ANALYSIS OF THE B-CLEAR STUDY William Jordan 1 , Jennifer Singh 1 , Shihyun You 1 , Ji Won Cremer 2 , Robert Elston 3 , Jared Delahaye 1 , Johannes Freudenberg 1 , Melanie Paff 1 and Dickens Theodore 2 , (1)GSK, Collegeville, PA, USA, (2)GSK, Durham, NC, USA, (3)GSK, Stevenage, Hertfordshire, UK Background: In the Phase 2b B-Clear study, 300 mg bepirovirsen (BPV