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This improved adhesion is crucial because it fosters the colonization of beneficial bacteria, which is necessary for maintaining gut homeostasis and supporting immune modulation which may be beneficial in alleviating conditions such as SLE (164)

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Class I ferroptosis stimulants are compounds targeting system Xc (e.g., erastin [43], sorafenib [7], sulfasalazine [44], and glutamate [43, 45]), while inhibitors directly targeting GPx4 (e.g., RAS selective lethality protein 3 [RSL3], ML-162) are considered as Class II ferroptosis inducers [3, 46, 47]