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Given the established role of immune dysfunction (including inflammatory cytokines, neuroinflammation, and immune cell abnormalities) in ME/CFS progression, the Low-dose Naltrexone for Post-COVID Fatigue Syndrome trial (NCT05430152) is currently exploring LDNs potential to reduce both fatigue and inflammation, thus providing a mechanistically grounded therapeutic approach

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Lutein supplementation reduces plasma lipid peroxidation and C-reactive protein in healthy nonsmokers

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