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Immunoprecipitation studies revealed an increased association of FUS with XRCC1, LigIII, and PARP-1, but not with other base excision repair (BER) proteins in ALS patient-derived iPSC lines carrying FUS mutations (R521H and P525L)

HCT 116 cells have been shown to accumulate 7-fold higher levels of copper compared to normal cells 39

273 Astrocytes infected with the virus demonstrated signs of reactivity, increased cytokine production and cellular stress

Barber, R

While abscopal responses (ARs) are thought to be immune-mediated, they remain a rare phenomenon in patients [109]

To validate these bioinformatics findings, mitochondrial function was assessed in LUAD cells following SLC25A39 knockout (KO)