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Targeting of miR9/NOTCH1 interaction reduces metastatic behavior in triple-negative breast cancer

2004 Dec;13(4):309-16

Unlike exogenously synthesized gRNA, this system synthesizes gRNA endogenously using tRNA and PtrpC promoters

Image Credit: l i g h t p o e t/Shutterstock.com Are side effects sometimes missed during clinical trials

The ACSL4LPCAT3 axis, by esterifying PUFAs like arachidonic acid into PC, generates a pro-ferroptotic lipid milieu

Finally, all processes in which neuroglia become reactive can induce a vicious circle of glial priming, i.e., the induction of hyperresponsiveness to further stimulation, resulting in a self-perpetuating cycle of CNS inflammation and/or functional incompetence