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[1] Retatrutide (trials): once-weekly subcutaneous administration, starting low (e.g., 2 mg) and escalating to 4, 8, or 12 mg maintenance, with slower titration used to improve tolerability

10.1016/j.bbapap.2005.08.018 84 NegreiraG

The weight sits atop the bone structure, and muscle retains the desired shape far better than fat and soft tissue

Without some form of biological stratification, their average benefit across unselected patient populations may not justify these costs

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