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Modulators of mitophagy, including PINK1/Parkin activators, may enhance the clearance of damaged mitochondria and promote antifungal immunity, although their therapeutic potential requires further validation (Qin et al., 2023)

A computational docking simulation using HDOCK on hBAX (PDB code 2K7W) and BNIP3-peptide 1-49 predicted an interaction with residues in BAX via -helix 5 and the N-terminal half of 1-2 loop, an important domain for its activation 37 (Fig

An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma

These ROS, often called free radicals, are highly unstable molecules that recklessly react with other molecules, which can damage your DNA, cells, and RNA, leading to inflammation and chronic health conditions, including headaches and migraine attacks

Gut microbial metabolites as multi-kingdom intermediates

Neurodegenerative diseases and oxidative stress