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Physiologically relevant LPS concentrations (010 ng/ml) can induce intestinal tight junction permeability in enterocytes via an increase in TLR-4 and CD14 expression, without inducing cell death 108

The disruption of these precisely regulated networks is now acknowledged as a causative element in both male and female infertility, leading to vigorous attempts to develop medications that either block pathogenic ncRNAs or restore protective ones

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