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MOTS-c is one of the several mitochondrial-derived peptides, including humanin and the SHLP family of peptides

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Majewski G, Widziewicz K, Rogula-Kozowska W, Rogula-Kopiec P, Kociszewska K, Rozbicki T, Majder-opatka M, Niemczyk M (2018) PM origin or exposure duration

In contrast, tissue infected with pyocyanin-deficient strains does not exhibit this accumulation (108)

Glutathione can help to get rid of free radicals before they cause cell damage

The regulation of many processes by O-GlcNAc modification has led to the comparison of O-GlcNAcylation to phosphorylation events and redox modification of proteins as a regulator of protein activity, with emphasis on the limited expression of enzymes involved in the regulation of O - GlcNAcylation versus the plethora of cellular kinases mediating phosphorylation events [217]