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Nutrients 9(5):521

In aged tendons, tenocyte activity is impaired, and functionally compromised pro-inflammatory tenocytes accumulate ( 9 Conclusion Tendon injury is a major musculoskeletal disorder that causes pain, limited activity, significant disability, and lost productivity

The cells were allowed to get adapted with the incubation conditions for 20 min before the addition of compounds to the incubation mixture

Perhaps the most promising to date, however, is ALDA-1, which was originally developed as a small molecule activator of ALDH2, but more recently has been shown to also activate ALDH1a1 with similar potency (239, 240)

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