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Clin Cancer Res 2011

As observed for plastidial class I GRXs, GRXS14 is formed by a single GRX domain whereas GRXS16 has a modular organization possessing an N-terminal domain (GIYYIG endonuclease fold) fused to one GRX domain [3, 62, 63]

By helping neutralize free radicals, glutathione may also help promote healthy aging.

In MDSCs, the activation of mGluR2/3 reduces the immunosuppressive properties of MDSCs on T cells and diminishes the effects of MDSCs in cancer cells [176, 177]