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Comprehensive Molecular and Immune Profiling of Non-Small Cell Lung Cancer and Matched Distant Metastases to Suggest Distinct Molecular Mechanisms Underlying Metastasis

The molecular gutliver signaling, we substantially revised the manuscript with detailed discussions of key pathways: TLR4/NF-B, MAPK signaling, tight junction regulation, microbial metabolite signaling (e.g., SCFAs), and cytokine cascades