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60 min before the formalin injection

Abstract N -nitrosamine (NA) impurities in pharmaceuticals represent cohort of concern compounds under ICH M7(R2), due to their mutagenic/carcinogenic potential, involving cytochrome P450 (CYP)-mediated metabolic activation

If this is the case, you might have an increased risk of having some kind of side effects or allergic reaction

Interestingly, Adriamycin, a representative anticancer drug, was added into the solution of ZnS QDs-GSH/L-Cys, the blue fluorescence of ZnS QDs-GSH/L-Cys was greatly enhanced instead of being quenched, which indicated that ZnS QDs-GSH/L-Cys can be used as an enhanced-fluorescence nanoprobe for determining Adriamycin

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