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While many supplements use reduced glutathione (L-glutathione), it is often broken down in the stomach before it can be absorbed

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For instance, cerium oxide and Prussian blue exhibit antioxidant properties due to their multienzyme activities similar to SOD and CAT, and simultaneously possess properties unique to nanomaterials such as high catalytic activity, good stability, and low cost [182]

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Tissue-Specific Accumulation : Research indicates this form preferentially accumulates in metabolically active tissues like the brain, liver, and lungs, where glutathione demand is highest for maintaining cellular function

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