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Adenosine triphosphate binding cassette subfamily C member 1 (ABCC1) overexpression reduces APP processing and increases alpha-versus beta-secretase activity, in vitro

Although the inhibition of CA9 did not affect the basal level of glycolysis, it significantly inhibited the gemcitabine-induced acceleration of extracellular acidification and mitochondrial functions in cancer cells, which was verified in xenografted mice