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ACS Nano 14 (9), 1122511237

Direct physical proteinprotein interactions have been demonstrated for many of these proteins, summarized in Figure 3, which also shows other documented functional integrations between IGF-1 and its key interacting proteins

Melatonin Many studies have shown that melatonin is a potent endogenous antioxidant [107], which also indirectly stimulates certain antioxidant enzymes such as SOD and Gpx4 [108]

1 2 3 "Review article: Systemic consequences of coeliac disease"

[87] found that ox-LDL stimulated in ECs NLRP3 inflammasome activation, increased IL-1 and IL-18 maturation and secretion, increased intracellular ROS and increased lactate dehydrogenase (LDH) release in ECs

Despite recognising B12's importance on the central nervous system, research into its potential role in sleep disorders and its impact on subjective sleep quality has been sparse and often contradictory