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First, our investigation of the mechanism of l-carnitine action on the AMPK-ACC-CPT1 signaling pathway in synovial membranes is not sufficiently in-depth and lacks high-quality evidence

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In addition, we found that changes in butyrylcarnitine were positively correlated with improvements in language index and RBANS composite score

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Of interest, the down-expression of ACC2 results from an epigenetic process linked to histone deacetylation at the ACACB promoter by Sirtuin 1/6 that are activated by high cytosolic NAD + levels associated with enhanced FAO and reduced glucose metabolism