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HCC is considered chemoresistant in humans although mitoxantrone has been reported to be helpful in some cases.7, 56, 57 The most likely reason for the poor response to systemic chemotherapy is the expression of P-glycoprotein in hepatocytes

78 These DAMPs play a major role in promoting neutrophil infiltration by activating antigen-presenting cells, including Kupffer cells and dendritic cells, which amplifies the immune response and the progression of liver injury

Research demonstrates effects on tendon-to-bone healing, ligament repair, muscle injury recovery, and joint-related inflammatory signaling

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Dietary Guidelines for Americans, 20202025

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