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Pycnogenol attenuates the inflammatory and nitrosative stress on joint inflammation induced by urate crystals

No tolerance development appears to occur, unlike many pharmaceutical compounds

HGF and SCF treatment reduced ROS levels, preserved mitochondrial membrane potential, and upregulated mitochondrial-related protein expression in hBM-MSCs

However, the function of GSR in liver cancer and sorafenib resistance is poorly elucidated

Fluorescence signals were measured at 500 nm excitation and 525 nm emission for intracellular ROS levels, and at 495 nm excitation and 515 nm emission for intracellular RNS levels, using multi-mode microplate reader (SpectraMax iD3, Molecular Devices, USA)

The relative gene expression level was calculated using the 2 -CT method (Lin et al