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doi:10.1007/s40279-016-0669-8

The S100 proteins are expressed in a cell- and tissue-specific manner and engaged in multiple functions in various cell types and tissues (23, 24)

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As well as when patients with -thal were exogenously supplemented with vitamin E, researchers found that antioxidants could mitigate oxidative stress in erythrocytes through multiple targets, thereby impacting iron overload ( On the other hand, iron overload may also be an intermediate link in the interaction between ferroptosis and, IE in -thal

In the present study, 1MEA cells, transformed by chronically exposing CL2 cells to 3MC, were found to be more susceptible to oxidative stress compared with CL2 cells, due to the decreased synthesis of GSH