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However, they are currently in preclinical or early clinical exploration stages and require more data to support their translational potential

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PubMed Aminian, A., Zajichek, A., Arterburn, D.E., Wolski, K.E., Brethauer, S.A., Schauer, P.R., et al

Furthermore, the study highlights that most trials have had extremely short follow-up periods (usually 824 weeks), which has hampered our understanding of the therapies long-term safety and sustained efficacy

Advanced formulation strategies are imperative to enhance its competitiveness against GLP-1RAs in obesity management (Fig

10.1016/S0006-291X(02)00430-8 175 NaharL.CharoensupR.KalievaK.HabibiE.GuoM.WangD.et al (2025)