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A.GrechA.BorelleS

High-fat diet promotes colorectal tumorigenesis through modulating gut microbiota and metabolites

However, certain SBA, such as hydroxydeoxycholic acid (HDCA), may partially counteract these effects by modulating gut microbiota composition and activating FXR to regulate lipid metabolism genes [65]

Here, we find that SUMOylation of TDP-43 occurs at K408 by SUMO2/3 in response to stress