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Rapid life-history evolution reinforces competitive asymmetry between invasive and resident species

Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans

Pfaus, J., Shadiack, A., Van Soest, T., Tse, M., & Molinoff, P

This finding suggests that the insertion of the octanoyl group into cavity II not only contributes to the binding of the ligand, but also helps to orient the N-terminus of ghrelin to cavity I, which is critical in receptor activation

This supports the observation that the R lines show much smaller phenotypic perturbation after Xcc infection compared with the S line

(C-E) Cell viability of cells treated with RSL3 or Erastin2 with or without ML225 pretreatment