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Many studies have shown that adipose tissue is not only the passive energy store, but also an active endocrine organ, producing biologically active substances like adipocytokines, leptin, adiponectin, resistin and angiotensin (1)

1i,j and Extended Data Fig

Moreover, they have attempted to identify the synergy between antibiotics and both conventional and unconventional agents, including bacteriophages

In a Phase II trial in pancreatic cancer patients, oral curcumin was well tolerated and showed some biological activity in a subset of patients, despite low systemic absorption (Dhillon et al., 2008)

While serious side effects like allergic reactions are rare, its important to monitor for any unusual symptoms.

It also differentiates painful versus painless DN, showing greater nerve loss in symptomatic patients [42]