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Effect of ALA supplementation on pathophysiological alterations in FRDA fibroblasts and iNs

Journal of Clinical Investigation, 1992

However, the clinical outcomes associated with deferiprone, an oral iron chelator, have been inconsistent

RNS-dependent mitigation of the negative outcomes of seed ageing persisted until the 21st day of accelerated ageing and was reflected in a higher germination rate of embryos and undisturbed growth of seedlings, compared to the aged and non-treated control

All lines of evidence indicate that fast and slow TGR inhibitors bind different conformational states present in the TGR enzymatic cycle induced by both NADPH-dependent reduction and the concomitant destabilization of the polypeptide chain, as shown by TSA

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