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The review documented DSIP's widespread distribution throughout the brain and peripheral tissues, its remarkably stable presence in cerebrospinal fluid, and its unusually long-lasting biological effects despite a short plasma half-life of only minutes

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In cases where the levels are dangerously low, thats when supplementation is recommended

Always start at the lowest dose that seems reasonable (like 12 mg) and increase if needed after a few nights

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Some researchers try to compensate by injecting more, figuring that extra volume will offset potency loss