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Toxicol Sci 162(2):462474

7E), indicating defective mitophagy

3 Drink once daily, preferably in the morning or mid-day for best absorption

Method Severe neonatal unconjugated hyperbilirubinemia (SNH) was induced in neonatal C57BL/6j mice model with phenylhydrazine (PHz) intoxication

Splicing occurs through XBP1 mRNA to the translation of sXBP1 protein, which is a transcription factor that induces genes involved in chaperoning proteins and degrades misfolded proteins in ER, thus triggering inflammatory reaction and promoting cell apoptosis mediated by apoptosis ASK1 and JNK [99, 102]