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Metabolomics in the study of retinal health and disease

Scientists have noted that the simplicity of the molecule gives consistent results across different experimental conditions and is stable under standard lab storage conditions

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This is the central scientific question, and the answer is: possibly in some experimental systems, but the evidence base is still narrow

AAV2-based vectors have been used in clinical trials to deliver therapeutic genes to the striatum or SNpc, showing safety and moderate benefit (Niethammer et al., 2017

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