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High-dose vitamin B12 therapy has been shown to be effective in reducing neuropathic pain in patients with diabetic neuropathy, highlighting its potential as a valuable treatment option . More research has looked at how different ways of taking B12 work

Contraindicated / avoid: personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2) based on a rodent thyroid C-cell tumor signal and known hypersensitivity to the drug

Multiple mechanisms may interrelate NNMTi treatment with the microbiome

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Researchers compared the levels of B12 in 70 migraine patients and 70 people who didnt experience migraines

This is a black box warning for the entire GLP-1 class based on thyroid C-cell tumor findings in rodent studies