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Kanase T, Guhey A, Gawas D

The in vitro results indicated that perillyl alcohol inhibited the NF-B pathway and promoted the nuclear translocation of Nrf2, thereby reducing the levels of proinflammatory cytokines (IL-1, IL-6, and TNF-), ROS, and COX-2 while increasing the viability of macrophages

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Mitochondrial Autophagy is a HIF-1-dependent Adaptive Metabolic Response to Hypoxia