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Abbreviations: AA amyloidosis: serum amyloid A amyloidosis, AL amyloidosis: immunoglobulin light chain amyloidosis, ATTR: transthyretin amyloidosis, BD: twice daily, GI: gastrointestinal, QID: four times daily, SIBO: small intestinal bacterial overgrowth, TDS: three times daily, TPN: total parenteral nutrition

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Factors such as dose-dependent adverse reactions, the inability to penetrate the BBB and achieve effective therapeutic concentrations, and variations in patient sensitivity and metabolic capacity may all influence outcomes