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doi: 10.1016/j.jocrd.2019.100481 [DOI] [Google Scholar] 25.Modarresi A, Chaibakhsh S, Koulaeinejad N, Koupaei SR

Due to its function as a damage-associated molecular pattern (DAMP) (53, 62, 63), pSYN might trigger and maintain a proinflammatory shift of the immune system

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Considering that AIF3 splicing caused mitochondrial complex disassembly and induced genes involved in OXPHOS and ROS pathways, we next examined the effect of AIF3 splicing on cellular ROS levels in WT and AIF3 splicing MEFs in the presence or absence of H 2 O 2 treatment (250 M, 2 h) using MitoSOX staining