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Kidney GSH also was maximal at 16 h and achieved 1.6-times control values

After being absorbed by HCC cells, the Cu 2+ and disulfide bond (-SS-) in MONs@MOF-199 nanoparticles react with GSH in a redox reaction, and the nanostructure collapses, releasing DOX and SOR to exude their anti-tumor effects

In addition, FIN56 is capable of binding and activating squalene synthase, and leads to depleting coenzyme Q10 (CoQ10) (Shimada et al., 2016), which is a vital antioxidant by directly reducing lipid peroxyl radicals (Ernster and Forsmark-Andree,1993)

10.1016/j.fsi.2023.108582 257 ZhuL.YuanY.YuanL.LiL.LiuF.LiuJ.et al (2020)

Animal protein in particular contains many nutrients the body needs (besides amino acids) for healthy thyroid function, including B12, selenium, iron, and zinc

iii) the sensory nerve fibers recover more rapidly, and therefore only the sural sensory nerve demonstrated significant treatment differences