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In this study by Fillon-Emery et al., a multivitamin with folic acid (the synthetic form) was shown to be effective in people with Down syndrome

(PubMed) Johansen JS, Harris AK, Rychly DJ, Ergul A

It is also advised to avoid mega doses of pyridoxine in pregnant or breastfeeding patients unless necessary, since safety data for doses beyond the recommended dietary allowance are limited

Tingling and Numbness: Often described as "pins and needles," these sensations in your hands and feet are a direct sign of nerve irritation

BMC Urol 5:18 Mostile G, Jankovic J (2009) Treatment of dysautonomia associated with Parkinsons disease

Company Profile Shimu group was founded in 2001, located in Shijiazhuang high-tech industrial zone, including Shijiazhuang Shimu Animal Pharmaceutical Co., Ltd, Hebei Tianqiong International Trade Co., Ltd, Hebei Huamu Tianhe Biological technology Co., Ltd, three pillar industries