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& Galvn, J

The size-effect of gold nanoparticles and nanoclusters in the Inhibition of amyloid- fibrillation

Briefly, cells were incubated with buffer-1 [10 mM HEPES/KOH (pH 7.8), 1.5 mM MgCl 2 , 10 mM KCl, 0.5 mM dithiothreitol, 0.2 mM phenylmethylsulfonyl fluoride, and 1 mM Na 3 VO 4 ] for 20 min

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The protection of the hearing function could be explained by a combined antioxidant, neuroprotective and anti-inflammatory effect complemented by the enhancement of the action of an endogenous hearing protection mechanism via DA release from LOC efferents, the effector arm of a feedback loop, that attenuates the excitotoxic overactivation of the primary auditory neurons and their synapses with the IHCs