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While these inherent properties make GO a promising antibacterial agent, its effectiveness can be further modulated by specific factors such as its size, shape, and surface functionality, each of which plays a critical role in determining its interactions with bacterial cells and overall antibacterial performance 46

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Key antioxidant enzymes, such as glutathione peroxidase (GPX1), glutathione reductase (GSR), superoxide dismutase (SOD1 and SOD2), and members of the thioredoxin family, exhibit reduced expression in oocytes from aged animals

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Increased intestinal translocation of immunogenic agents, including microbes and dietary components, induces inflammation and increases the risk of developing autoimmunity or other non-infectious diseases (Table 2)

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