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As the crucial upstream node of SLC7A11/GSH/GPX4 signaling pathway, the inhibition of SLC7A11 leads to impaired antioxidant capacity, depleted GSH, inactivated GPX4, increased lipid ROS, ultimately induces ferroptosis in cancer cells (Jiang et al, 2021)

Review of N-acetylcysteine for the treatment of acetaminophen (paracetamol) toxicity in pediatrics

Administer Glucagon For individuals with diabetes, glucagon injection can be administered if they have become unconscious or are unable to consume carbohydrates

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This uncertainty makes dose adjustment decisions difficult and can lead to unnecessary discontinuation of a compound that was not responsible

Buchet & Lauwerys, 1981