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I got my first shot on February 8th (Pfizer) and experienced some muscle twitching in both legs while I was falling asleep but I havent had them since so Im guessing it was a minor side effect to the shot

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This difference becomes even more pronounced during pregnancy, when fat mass increases to approximately 19.8 kg at full term (Duan et al

Patch test 24 hours prior to full application to assess sensitivity