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6k) due to reduced NAD + regeneration which resulted in a lower NAD + /NADH ratio (Fig

Demyelination induces axonal defects, such as nodal complex alterations, conduction blocks, and/or irreversible axon losses that clearly disrupt long-range connectivity (Nave, 2010), as in multiple sclerosis (MS), an autoimmune disease targeting OLGs

Muscle Satellite Cells and Aging While initially targeted at fat, NNMT inhibitors have shown surprising potential in muscle tissue

This was a distasteful commutation

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