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Ferroptosis and PAGln-mediated collagen deposition impair electrical conduction through fibrosis and loss of ion channels[78]

PMID: 11347722

SA-induced S-nitrosylation of several other key proteins that are reported to be involved in the AD pathogenesis, such as protein kinase c (PKC) [71,72,73,74, 94], cullin-5 [95], and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [96, 97]

chuanxiong extracts enriched in ligustilide and ferulic acid extended lifespan by about 16% and reduced ROS accumulation, while improving mitochondrial integrity and neuronal regeneration [75,76,86,87,88]