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When designing an amylin-analog it was important to address the aggregatory nature of this protein

COSMAX provides a structured environment where these different elements can be managed within a single development pipeline

[3] So the two molecules embody two strategies that converged on the same goal from opposite engineering philosophies: cagrilintide adds a separate hormone (amylin) intended to be combined with an incretin, while retatrutide packs an additional receptor activity (glucagon) into the incretin molecule itself