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While PPAR is predominantly expressed in adipose tissue, the ectopic induction of PPAR is observed in the steatotic liver

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In ovulation-induction and ART settings, MI, alone or as discussed previously, in physiologic combination with D-chiro-inositol (typically 40:1), has been associated with higher clinical pregnancy rates, improved oocyte/embryo quality, and lower gonadotropin requirements (154)