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In addition, VGB4 inhibited VEGF-A-induced sprouting angiogenesis in collagen matrix with the maximum reduction effect on sprout number by 67.5% and 84.1% at 0.55 M and 0.74 M, respectively, as compared to control and scr ( P 0.001) (Fig

All these parameters may contribute to explain the lack of reproducibility between studies, and standardizing data records may help alleviate this issue in future studies

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The overlap in anti-fibrotic and anti-oxidative pathways strengthens the biological plausibility of MSC-based rejuvenation, yet the two studies diverge on safety assumptions

29 Another study posited that DMF could potentially attenuate recurrence of stenosis after acute vascular injury