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10.1074/jbc.272.46.28869 203 ZhangJ.FergusonS

The neuroprotective effects of the ketogenic diet further extend to synaptic plasticity regulation: by increasing -hydroxybutyrate (BHB) levels, it directly activates the ERK/CREB signaling pathway in the hippocampus, promoting brain-derived neurotrophic factor (BDNF) synthesis (especially in females) to restore impaired long-term potentiation (LTP) in Alzheimers model mice

The Effect of Alpha-Lipoic Acid on Blood Pressure in Type 2 Diabetics

Sleep disturbance is also common in postmenopausal women 3 , with some studies showing that up to half of women experiencing a dramatic increase in sleep disturbance during the transition from perimenopause to menopause